Spiers P S, Onstad L, Guntheroth W G
Department of Pediatrics, School of Medicine, University of Washington, Seattle, USA.
Am J Epidemiol. 1996 Jun 1;143(11):1137-41. doi: 10.1093/oxfordjournals.aje.a008691.
It was hypothesized that a short interpregnancy interval immediately following the birth of an infant that had succumbed to sudden infant death syndrome (SIDS) (and no other cause of death) would be associated with a reduced mean birth weight in the next infant. Mothers who had given birth to two children in the state of Oregon between 1975 and 1984 and whose first child had died in infancy from either SIDS (n = 84) or some other cause (n = 305) were identified from vital records. A multiple regression analysis in which adjustment was made for possible confounding variables (including the birth weight of the deceased child) was conducted. When the firstborn child had succumbed to SIDS, the mean birth weight of the next baby was 314 g (2,978 g vs. 3,292 g, p = 0.04) lower when the interpregnancy interval was less than 6 months versus greater than 6 months. In contrast, a less-than-6-month interval had a slightly positive effect (60 g) on the mean birth weight of the next baby when the firstborn child had died due to a cause other than SIDS. These results suggest that parents who have lost a child to SIDS may wish to delay a new pregnancy for at least 6 months.
研究假设，在因婴儿猝死综合征（SIDS）（且无其他死因）夭折的婴儿出生后紧接着的短生育间隔，会与下一胎婴儿的平均出生体重降低有关。从生命记录中识别出1975年至1984年间在俄勒冈州生育了两个孩子、且其第一个孩子在婴儿期死于SIDS（n = 84）或其他原因（n = 305）的母亲。进行了多元回归分析，对可能的混杂变量（包括夭折孩子的出生体重）进行了调整。当第一个孩子死于SIDS时，生育间隔小于6个月的下一胎婴儿的平均出生体重比生育间隔大于6个月的低314克（2978克对3292克，p = 0.04）。相比之下，当第一个孩子因SIDS以外的原因死亡时，小于6个月的生育间隔对下一胎婴儿的平均出生体重有轻微的正向影响（60克）。这些结果表明，因SIDS失去孩子的父母可能希望将再次怀孕推迟至少6个月。
