Dominguez N E, Thomas C J, Gerzina T M
School of Dental Studies, University of Sydney, Australia.
Int J Prosthodont. 1996 Mar-Apr;9(2):137-41.
Interim soft denture liners or conditioners may be valuable therapeutic materials. The life of these liners varies, but it can be extended by the use of a poly(methyl methacrylate) coating material (Monopoly). This study evaluated the ability of Monopoly to prevent water absorption and plasticizer loss from an underlying tissue conditioner (Visco-gel). Disk specimens of Visco-gel coated with Monopoly were immersed in water that was sampled at 24 hours, 1 week, 2 weeks, and 1 month. Uncoated Visco-gel samples acted as controls. Water absorption was determined gravimetrically at each time interval and decanted water was subjected to separation by reversed phase high-performance liquid chromatography for component identification. All samples suffered significant initial weight loss followed by a trend toward weight gain in the uncoated control group, probably because of water absorption. The Monopoly coating appeared to reduce this effect. Plasticizer loss from the tissue conditioner was below quantifiable limits by high-performance liquid chromatography, but methyl methacrylate monomer loss from the Monopoly coating was demonstrated. Some clinical implications are discussed.
临时软性义齿衬垫或调理剂可能是有价值的治疗材料。这些衬垫的使用寿命各不相同，但可通过使用聚甲基丙烯酸甲酯涂层材料（Monopoly）来延长。本研究评估了Monopoly防止底层组织调理剂（Visco-gel）吸水和增塑剂损失的能力。涂有Monopoly的Visco-gel圆盘标本浸泡在水中，分别在24小时、1周、2周和1个月时取样。未涂层的Visco-gel样品作为对照。在每个时间间隔通过重量法测定吸水率，将倒出的水通过反相高效液相色谱法进行分离以鉴定成分。所有样品最初均出现显著的重量损失，随后未涂层对照组有重量增加的趋势，这可能是由于吸水所致。Monopoly涂层似乎减少了这种影响。通过高效液相色谱法测定，组织调理剂中的增塑剂损失低于可量化的限度，但证实了Monopoly涂层中有甲基丙烯酸甲酯单体损失。文中讨论了一些临床意义。
