Wolff M S, Daum S M, Lorimer W V, Selikoff I J
J Toxicol Environ Health. 1977 May;2(5):997-1005. doi: 10.1080/15287397709529498.
Subcutaneous fat samples from 25 workers in a styrene polymerization plant have been analyzed for styrene, ethyl benzene, toluene, benzene, and benzaldehyde by gas chromatography. Styrene was found in samples from 13 of 17 workers who had been heavily exposed within the previous 3 days, 5 of 13 having been exposed 2-3 days earlier. Six workers 4-90 days removed from exposure and two 2-3 days removed from low (less than 5 ppm) exposures had no detectable styrene in fat tissue samples. Toluene and ethyl benzene were found in varying amounts in many samples, and benzene was observed in three samples. Benzaldehyde was observed at levels of 5-53 microng/g in all samples. Although urinary metabolites and breath levels of styrene are reported to be detectable for less than 24 hr following exposure, styrene was found in subcutaneous fat from the subjects of this study for as long as 3 days after the most recent occupational exposure. The combination exposures in such a setting are reflected in the variety of hydrocarbons found in fat samples of workers.
对一家苯乙烯聚合厂的25名工人的皮下脂肪样本进行了气相色谱分析，以检测其中的苯乙烯、乙苯、甲苯、苯和苯甲醛。在之前3天内曾大量接触苯乙烯的17名工人中，有13人的样本中检测到苯乙烯，其中5人在2至3天前接触过苯乙烯。6名在脱离接触4至90天的工人以及2名在脱离低（低于5 ppm）接触2至3天的工人的脂肪组织样本中未检测到苯乙烯。许多样本中都检测到了不同含量的甲苯和乙苯，有三个样本中检测到了苯。所有样本中苯甲醛的含量为5至53微克/克。尽管据报道，接触苯乙烯后24小时内尿液代谢物和呼出气体中的苯乙烯含量可被检测到，但在本研究对象的皮下脂肪中，即使在最近一次职业接触后长达3天仍能检测到苯乙烯。在这种环境下的混合接触情况反映在工人脂肪样本中发现的各种碳氢化合物上。
