Grønbaek M N, Deis A, Sørensen T I, Becker P U, Schnohr P, Jensen G B
Institut for sygdomsforebyggelse, center for epidemiologisk grundforskning, Kommunehospitalet, København.
Ugeskr Laeger. 1996 Apr 15;158(16):2258-61.
In a prospective population study of 7,234 women and 6,051 men aged 30-79 years, information on beer, wine, spirits and tobacco consumption, and on education, income and body mass index were assessed in the period 1976-1978, and the population was followed until 1.1.1988 for mortality. With increasing intake, the wine-mortality risk function steadily decreased from a relative risk of 1.00 for those who never drank wine through 0.51 (95% confidence limits; 0.32-0.81) among those who drank three to five glasses per day. In contrast, neither beer nor spirits consumption was associated with reduced risk. For spirits consumption the relative risk of dying increased from 1.00 among those who never drank to 1.34 (1.05-1.71) among those with an intake of 3-5 drinks per day. Wine drinking showed the same relation to risk of death from cardio- and cerebrovascular disease as to mortality from all causes.
在一项针对7234名年龄在30至79岁之间的女性和6051名男性的前瞻性人群研究中，于1976年至1978年期间评估了关于啤酒、葡萄酒、烈酒和烟草消费以及教育程度、收入和体重指数的信息，并对该人群进行随访直至1988年1月1日以获取死亡率数据。随着摄入量的增加，葡萄酒 - 死亡率风险函数稳步下降，从不饮酒者的相对风险为1.00，到每天饮用三至五杯葡萄酒的人群中相对风险为0.51（95%置信区间：0.32 - 0.81）。相比之下，啤酒和烈酒消费均与风险降低无关。对于烈酒消费，死亡的相对风险从从不饮酒者的1.00增加到每天摄入3 - 5杯者的1.34（1.05 - 1.71）。饮用葡萄酒与心血管和脑血管疾病死亡风险的关系与全因死亡率的关系相同。
