Massone L, Anonide A, Borghi S, Usiglio D
Department of Dermatology, Galliera Hospital, Genoa, Italy.
Int J Dermatol. 1996 Mar;35(3):177-80. doi: 10.1111/j.1365-4362.1996.tb01634.x.
Phenolformaldehyde resins, especially the para-tertiary-butylphenolformaldehyde resin (PTBP-FR), are widely used in industry and in numerous materials of everyday use, such as glues, adhesives, or inks. They can cause many occupational and nonoccupational cases of dermatitis.
Forty-one patients with positive patch test results to PTBP-FR were selected for this study. They were patch-tested with a series of chemically related compounds and cross-reactions were noted.
Phenolformaldehyde resin (PF-R) was frequently positive (65.8%), whereas other compounds gave a much smaller number of positive results. Cases of occupational exposure (24.4%), location of the dermatitis (hands were involved in 46.3% of cases), and possible sources of exposure (shoes were the responsible agent in 12.2% of cases) were evaluated.
Phenolformaldehyde resins are an important cause of contact dermatitis and must be studied chemically and clinically to improve the prognosis of sensitized patients.
酚醛树脂，尤其是对叔丁基酚醛树脂（PTBP - FR），广泛应用于工业及众多日常用品中，如胶水、粘合剂或油墨。它们可导致许多职业性和非职业性的皮炎病例。
本研究选取了41例对PTBP - FR斑贴试验结果呈阳性的患者。他们接受了一系列化学相关化合物的斑贴试验，并记录交叉反应情况。
酚醛树脂（PF - R）常常呈阳性（65.8%），而其他化合物呈阳性的结果要少得多。对职业暴露病例（24.4%）、皮炎发生部位（手部受累占46.3%的病例）以及可能的暴露源（鞋子是12.2%病例的致病因素）进行了评估。
酚醛树脂是接触性皮炎的一个重要病因，必须从化学和临床方面进行研究，以改善致敏患者的预后。
