Höffken H, Otto K, Soost H J
J Histochem Cytochem. 1979 Jan;27(1):19-24. doi: 10.1177/27.1.86561.
For automated prescreening methods by high resolution analysis serving as a detecting method in gynecologic mass screening programs a new monolayer deposition method of cervical material has been used. This method will be outlines briefly and the mode of evaluation as well as current cytomorphological findings will be presented. With regard to measurability of the slides prepared according to the new method a number of cytologic criteria were thought to be of particular importance. These criteria are delineated and compiled in a table. A form in which these criteria were listed was filled in by cytopathologists for each slide evaluated. When performing isolation and centrifugation procedures several new morphologic questions arose to the cytopathologist which can only partly be answered by now. If taking into account all criteria of evaluation it may be followed from the present experiences that slides of cervical material are much more suited for automated prescreening methods by high resolution analysis if prepared after isolation and centrifugation in macromolecular liquids than are conventional Papanicolaou smears or slides from suspensions with isolated cells that were not subjected to centrifugation procedures.
在妇科肿块筛查项目中，作为一种检测方法，高分辨率分析的自动预筛查方法采用了一种新的宫颈材料单层沉积方法。本文将简要概述该方法，并介绍评估模式以及当前的细胞形态学发现。关于根据新方法制备的玻片的可测量性，一些细胞学标准被认为特别重要。这些标准在一个表格中进行了描述和汇总。细胞病理学家为每张评估的玻片填写了一份列出这些标准的表格。在进行分离和离心程序时，细胞病理学家遇到了几个新的形态学问题，目前只能部分回答。如果考虑到所有评估标准，从目前的经验可以推断，与传统巴氏涂片或未经过离心程序的分离细胞悬液制成的玻片相比，宫颈材料玻片在大分子液体中进行分离和离心后制备，更适合通过高分辨率分析进行自动预筛查。
