大鼠10号染色体的遗传、物理及比较图谱。
A genetic, physical, and comparative map of rat chromosome 10.
作者信息
Yeung R S, Buetow K H, Scherpbier-Heddema T, Bell D W, Testa J R
机构信息
Division of Medical Sciences, Fox Chase Cancer Center, Philidelphia, Pennsylvania 19177, USA.
出版信息
Mamm Genome. 1996 Jun;7(6):425-8. doi: 10.1007/s003359900126.
A map of rat Chromosome (Chr) 10 was generated from 21 markers, mostly of conserved structural genes, by linkage analysis and fluorescence in situ hybridization. The study emphasizes the proximal third of the chromosome which, until now, has been relatively devoid of markers. Based on comparative analysis, our data suggest that genes on rat Chr 10 are conserved on mouse Chr 11, 16, 17 and human Chr 16, 5, and 17.
通过连锁分析和荧光原位杂交技术，利用21个标记（大多数为保守结构基因）构建了大鼠10号染色体（Chr）图谱。该研究着重关注了该染色体近端的三分之一区域，到目前为止，该区域相对缺乏标记。基于比较分析，我们的数据表明大鼠Chr 10上的基因在小鼠Chr 11、16、17以及人类Chr 16、5和17上是保守的。
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