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Assignment of 22 loci in the rat by somatic hybrid and linkage analysis.

作者信息

Yeung R S, Hino O, Vilensky M, Buetow K, Szpirer C, Szpirer J, Klinga-Levan K, Levan G, Knudson A G

机构信息

Fox Chase Cancer Center, Department of Surgical Oncology, Philadelphia, Pennsylvania 19111.

出版信息

Mamm Genome. 1993;4(10):585-8. doi: 10.1007/BF00361389.

DOI:10.1007/BF00361389
PMID:8268657
Abstract

Twenty structural genes and two unique anonymous DNA fragments have been mapped in the rat (Rattus norvegicus) with a panel of mouse x rat hybrids and linkage analysis. Ten of the 20 autosomes are represented by at least one of these markers. A new syntenic relationship among rat Chromosome (Chr) 16, mouse Chr 14, and human Chr 10q was established. Results of this study further support the extensive conservation of synteny between the rat and mouse and, to a lesser degree, between rat and human.

摘要

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本文引用的文献

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Spontaneous and radiation-induced renal tumors in the Eker rat model of dominantly inherited cancer.在显性遗传癌症的埃克大鼠模型中自发和辐射诱导的肾肿瘤。
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Mamm Genome. 1994 Nov;5(11):712-6. doi: 10.1007/BF00426078.
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Regional localization of rat peripheral myelin protein 22 (Pmp22) gene to chromosome 10q22 by FISH.
Mamm Genome. 1995 Jul;6(7):489. doi: 10.1007/BF00360665.
通过小鼠-大鼠体细胞杂交进行大鼠基因定位：白蛋白和甲胎蛋白基因的同线性及定位于第14号染色体
Cytogenet Cell Genet. 1984;38(2):142-9. doi: 10.1159/000132047.
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A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization.一个在生长、分化过程中以及细胞去极化后与c-fos共同调控的锌指编码基因。
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Chromosomal mapping of genes involved in growth control.参与生长控制的基因的染色体定位。
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Localization of the gene for familial adenomatous polyposis on chromosome 5.家族性腺瘤性息肉病基因在5号染色体上的定位。
Nature. 1987;328(6131):614-6. doi: 10.1038/328614a0.
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