Doyle S J, Hynes E, Naroo S, Shah S
Optimax Laser Eye Clinic, Manchester.
Br J Ophthalmol. 1996 Jan;80(1):25-8. doi: 10.1136/bjo.80.1.25.
AIMS/BACKGROUND: Keratoconus is generally held to be an absolute contraindication for photorefractive keratectomy (PRK). Corneas with inferior steepening on corneal topography are widely thought to have subclinical keratoconus. We were not convinced that this is always the case, as there seems to be a group of patients with a stable inferior steepening pattern on topography who show no other characteristics of clinical keratoconus. We thus decided to offer PRK to some of these patients under strictly defined criteria.
Four myopic patients with a topography pattern of inferior steepening were submitted to PRK. They were selected on the basis of being aged over 35, with a stable refraction, no slit-lamp signs of keratoconus, and a corrected vision of not less than 6/7 (0.9) with a spherical spectacle correction. They gave fully informed consent that this was an experimental procedure.
The refractive results at 6 months after operation were within the range one would expect for PRK on corneas with a regular 'bow-tie' topography and similar level of myopia. No unusual problems were encountered.
We feel that the corneal topography pattern of inferior steepening is not always a contraindication for PRK. The concept of a physiological 'displaced apex syndrome' is discussed and illustrated by corneal topography in different positions of gaze.
目的/背景:圆锥角膜通常被认为是准分子激光原位角膜磨镶术(PRK)的绝对禁忌证。角膜地形图显示下方陡峭的角膜被广泛认为存在亚临床圆锥角膜。我们并不确信情况总是如此,因为似乎有一组患者在地形图上呈现稳定的下方陡峭模式,但未表现出临床圆锥角膜的其他特征。因此,我们决定在严格定义的标准下为其中一些患者提供PRK手术。
对4例角膜地形图显示下方陡峭的近视患者实施PRK手术。入选标准为年龄超过35岁、屈光稳定、裂隙灯检查无圆锥角膜体征、球面眼镜矫正后矫正视力不低于6/7(0.9)。他们充分知情同意这是一项实验性手术。
术后6个月的屈光结果在具有规则“领结”形地形图且近视程度相似的角膜行PRK手术预期的范围内。未遇到异常问题。
我们认为角膜地形图显示下方陡峭的模式并不总是PRK手术的禁忌证。文中讨论了生理性“移位顶点综合征”的概念,并通过不同注视位置的角膜地形图进行了说明。