芽殖酵母中细胞类型决定的分子机制。

Molecular mechanisms of cell-type determination in budding yeast.

作者信息

Johnson A D

机构信息

Department of Microbiology and Immunology, University of California, San Francisco 94143, USA.

出版信息

Curr Opin Genet Dev. 1995 Oct;5(5):552-8. doi: 10.1016/0959-437x(95)80022-0.

DOI:10.1016/0959-437x(95)80022-0

PMID:8664541

Abstract

Studies of cell-type determination in the yeast Saccharomyces cerevisiae have revealed a regulatory network of proteins that are highly conserved in evolutionary terms. In the past few years, genetic, biochemical, and structural approaches have shown what many of these components do, how they fit together, and how they cooperate to regulate the expression of many different target genes.

摘要

对酿酒酵母细胞类型决定的研究揭示了一个在进化上高度保守的蛋白质调控网络。在过去几年中，遗传学、生物化学和结构学方法已经表明了这些组分中的许多组分的作用、它们如何组合在一起以及它们如何协同调节许多不同靶基因的表达。