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[捷克共和国根除脊髓灰质炎的努力]

[Efforts to eradicate poliomyelitis in the Czech Republic].

作者信息

Koza J

机构信息

Státní zdravotní ustav, Praha.

出版信息

Epidemiol Mikrobiol Imunol. 1996 Mar;45(1):11-4.

PMID:8665100
Abstract

The Czech Republic is one of the first countries where the paralytic form of poliomyelitis was eradicated by vaccination with the live attenuated vaccine. The effectiveness of vaccination was monitored every year up to 1992 by assessment of the immunity against polioviruses in a large group of sera from volunteers (cca 1500 subjects). This made it possible to improve occasional drops of immunity of the population, in particular in type 3. However, the absence of the paralytic form of poliomyelitis does not imply eradication of poliomyelitis which means elimination of wild polioviruses from the circulation in the population of a country. The circulation of wild polioviruses is monitored in the Czech Republic in cases of acute mild pareses, in particular, however, in waste waters of some large towns. A wild poliovirus was not detected so far. These investigations must started and be conducted up to the time when the Czech Republic will be granted the status of "country with eradicated poliomyelitis".

摘要

捷克共和国是最早通过接种减毒活疫苗根除麻痹型脊髓灰质炎的国家之一。直到1992年,每年都通过评估一大组志愿者血清(约1500名受试者)对脊髓灰质炎病毒的免疫力来监测疫苗接种的效果。这使得有可能改善人群中偶尔出现的免疫力下降情况,尤其是3型。然而,麻痹型脊髓灰质炎的消失并不意味着脊髓灰质炎的根除,脊髓灰质炎的根除意味着在一个国家的人群中消除野生脊髓灰质炎病毒的传播。在捷克共和国,对急性轻度麻痹病例,特别是一些大城市的污水中监测野生脊髓灰质炎病毒的传播情况。到目前为止尚未检测到野生脊髓灰质炎病毒。这些调查必须持续进行,直到捷克共和国被授予“脊髓灰质炎已根除国家”的地位。

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