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[巨细胞病毒性结肠炎与免疫功能正常患者首次发作的溃疡性结肠炎的关联]

[Association of cytomegalovirus colitis and the 1st episode of ulcerative colitis in an immunocompetent patient].

作者信息

Maté del Tío M, Peña Sánchez de Rivera J M, Larrauri Martínez J, Garcés Jiménez M C, Barbado Hernández F J

机构信息

Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid.

出版信息

Gastroenterol Hepatol. 1996 Apr;19(4):206-7.

PMID:8665359
Abstract

Colitis by cytomegalovirus (CMV) is an inflammation of the large bowel which leads to mucous and submucous ulceration producing bloody diarrhea of uncertain evolution. This disease is well known in immunosuppressed (IS) patients but is very rare in immunocompetent (IC) patients, particularly in association with the initiation of the ulcerative colitis (UC). The case of an immunocompetent male who developed UC following colitis by primary CMV is presented. Although the immunologic mechanism of UC is undoubtable, this case suggests the possibility of CMV being a triggering factor of UC.

摘要

巨细胞病毒(CMV)引起的结肠炎是一种大肠炎症,可导致黏膜和黏膜下溃疡,进而引发病情发展不确定的血性腹泻。这种疾病在免疫抑制(IS)患者中较为常见,但在免疫功能正常(IC)的患者中非常罕见,尤其是在与溃疡性结肠炎(UC)发病相关时。本文报告了一例原发性CMV结肠炎后发生UC的免疫功能正常男性病例。尽管UC的免疫机制毋庸置疑,但该病例提示CMV可能是UC的触发因素。

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