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[巨细胞病毒性结肠炎与免疫功能正常患者首次发作的溃疡性结肠炎的关联]

[Association of cytomegalovirus colitis and the 1st episode of ulcerative colitis in an immunocompetent patient].

作者信息

Maté del Tío M, Peña Sánchez de Rivera J M, Larrauri Martínez J, Garcés Jiménez M C, Barbado Hernández F J

机构信息

Servicio de Medicina Interna, Hospital Universitario La Paz, Madrid.

出版信息

Gastroenterol Hepatol. 1996 Apr;19(4):206-7.

PMID:8665359
Abstract

Colitis by cytomegalovirus (CMV) is an inflammation of the large bowel which leads to mucous and submucous ulceration producing bloody diarrhea of uncertain evolution. This disease is well known in immunosuppressed (IS) patients but is very rare in immunocompetent (IC) patients, particularly in association with the initiation of the ulcerative colitis (UC). The case of an immunocompetent male who developed UC following colitis by primary CMV is presented. Although the immunologic mechanism of UC is undoubtable, this case suggests the possibility of CMV being a triggering factor of UC.

摘要

巨细胞病毒(CMV)引起的结肠炎是一种大肠炎症,可导致黏膜和黏膜下溃疡,进而引发病情发展不确定的血性腹泻。这种疾病在免疫抑制(IS)患者中较为常见,但在免疫功能正常(IC)的患者中非常罕见,尤其是在与溃疡性结肠炎(UC)发病相关时。本文报告了一例原发性CMV结肠炎后发生UC的免疫功能正常男性病例。尽管UC的免疫机制毋庸置疑,但该病例提示CMV可能是UC的触发因素。

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[Association of cytomegalovirus colitis and the 1st episode of ulcerative colitis in an immunocompetent patient].[巨细胞病毒性结肠炎与免疫功能正常患者首次发作的溃疡性结肠炎的关联]
Gastroenterol Hepatol. 1996 Apr;19(4):206-7.
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引用本文的文献

1
CMV Colitis in Immunocompetent Patients: 2 Cases of a Diagnostic Challenge.免疫功能正常患者的巨细胞病毒性结肠炎:2例诊断难题
Case Rep Gastrointest Med. 2016;2016:4035637. doi: 10.1155/2016/4035637. Epub 2016 Apr 12.
2
Cytomegalovirus infection associated with onset of ulcerative colitis.巨细胞病毒感染与溃疡性结肠炎的发病相关。
BMC Res Notes. 2013 Feb 2;6:40. doi: 10.1186/1756-0500-6-40.
3
Possible role of human cytomegalovirus in pouchitis after proctocolectomy with ileal pouch-anal anastomosis in patients with ulcerative colitis.人类巨细胞病毒在溃疡性结肠炎患者行直肠结肠切除回肠储袋肛管吻合术后储袋炎中的可能作用。
World J Gastroenterol. 2007 Feb 21;13(7):1085-9. doi: 10.3748/wjg.v13.i7.1085.
4
Primary infection with cytomegalovirus in ulcerative colitis.
Dig Dis Sci. 2006 Dec;51(12):2184-7. doi: 10.1007/s10620-006-9474-9. Epub 2006 Nov 22.