Wong D A, Davis E M, LeBeau M, Springer T A
Center For Blood Research, Harvard Medical School, Boston, MA 02115, USA.
Gene. 1996 Jun 1;171(2):291-4. doi: 10.1016/0378-1119(95)00869-1.
We isolated a partial genomic clone encoding ITGAD, a novel beta 2-integrin alpha subunit. The ITGAD gene is highly homologous to the three previously known alpha subunit-encoding genes, that compose the beta 2 integrin family, in deduced amino acid sequence, intron/exon structure and mapping location (chromosome 16p11).
我们分离出了一个编码ITGAD(一种新型β2整合素α亚基)的部分基因组克隆。ITGAD基因在推导的氨基酸序列、内含子/外显子结构和定位位置(染色体16p11)方面,与之前已知的构成β2整合素家族的三个α亚基编码基因高度同源。