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[可能预测哮喘症状的酸碱滴定法参数:临床与统计学研究]

[pH-metric parameters potentially predictive of asthmatic symptomatology: clinical and statistical research].

作者信息

Ponticelli A, Capitanucci M L, Iacobelli B D, Nappo S

机构信息

Divisione di Chirurgia Pediatrica, Ospedale "Bambino Gesu" di Roma, Italia.

出版信息

Pediatr Med Chir. 1995 Nov-Dec;17(6):513-4.

PMID:8668585
Abstract

The gastro-esophageal reflux (GER) usually causes digestive symptoms, failure to trive and/or respiratory symptoms. Furthemore the association between GER and asthma is well known. Nevertheless, the relationship between two pathologies and role of GER in aggravation of asthma are not well known. The aims of our study is to identify the peculiar pH-metric caracteristics of GER may be responsable of asthmatic symptoms in children. The study was conducted in 32 children. The patients were divided into two groups: Group A composed of 16 children suffering from non-allergic asthma characterized by prevalent nocturnal manifestation; Group B composed of 16 children suffering from GER, without respiratory symptoms. All patients underwent to 21 pH-monitoring. The pH-metric data collected in two groups are submitted to statistic analysis using the Student's "t" Test.

摘要

胃食管反流(GER)通常会引起消化症状、生长发育不良和/或呼吸道症状。此外,GER与哮喘之间的关联是众所周知的。然而,这两种病症之间的关系以及GER在哮喘加重中的作用尚不清楚。我们研究的目的是确定GER可能导致儿童哮喘症状的特殊pH值特征。该研究对32名儿童进行。患者被分为两组:A组由16名患有以夜间发作为主的非过敏性哮喘的儿童组成;B组由16名患有GER但无呼吸道症状的儿童组成。所有患者均接受了21次pH监测。两组收集的pH值数据使用学生“t”检验进行统计分析。

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