涂片质量对宫颈细胞学显著异常检出率的影响。
Influence of smear quality on the rate of detecting significant cervical cytologic abnormalities.
作者信息
Henry J A, Wadehra V
机构信息
Department of Clinical Cytology, Newcastle General Hospital, Newcastle upon Tyne, UK.
出版信息
Acta Cytol. 1996 May-Jun;40(3):529-35. doi: 10.1159/000333910.
OBJECTIVE
To determine the correlation between cervical smear quality and the rate of detecting significant epithelial abnormalities.
STUDY DESIGN
Smear quality was assessed routinely in a series of 68,328 cervical spatula and spatula/brush combination smears received by our laboratory during 1993. Quality was assessed using a semiquantitative method, evaluating the presence of endocervical cells, metaplastic squamous cells, endocervical mucus and overall squamous cellularity.
RESULTS
Smear quality was graded as unsatisfactory, poor (18,680 smears), fair (9,739 smears) or good (39,909 smears); unsatisfactory smears were eliminated from the analysis. There was a highly significant correlation between smear quality and the rate of detecting significant epithelial abnormalities (chi 2=127.52, df=2, P<.001).
CONCLUSION
Smear quality is an important issue. Many significant abnormalities are potentially missed because of poor smear quality.
目的
确定宫颈涂片质量与检测到明显上皮异常的比率之间的相关性。
研究设计
1993年，对本实验室收到的一系列68328份宫颈刮板涂片和刮板/刷子联合涂片进行常规涂片质量评估。采用半定量方法评估质量，评估宫颈管细胞、化生鳞状细胞、宫颈管黏液和总体鳞状细胞数量的存在情况。
结果
涂片质量分为不满意、差（18680份涂片）、一般（9739份涂片）或好（39909份涂片）；不满意的涂片被排除在分析之外。涂片质量与检测到明显上皮异常的比率之间存在高度显著的相关性（χ²=127.52，自由度=2，P<0.001）。
结论
涂片质量是一个重要问题。由于涂片质量差，许多明显的异常可能会被漏检。
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