Savina N P, D'iakova A M, Liasko L I
Radiats Biol Radioecol. 1996 Mar-Apr;36(2):278-83.
In hybrid mice it was shown that the local irradiation of zones of thymus, hypothalamus-hypophysis (0.5, 1 and 10 Gy in both cases) and gonads (10 Gy) resulted in significant increase in weight at long terms after irradiation. In animals with increased weight the amount of lipids raised, balance of hormones and state of thymus-dependent unit of immune system changed, and exterior symptoms of early aging were observed. After irradiation of spleen and thigh muscles (10 Gy in both cases) all indices at the same period corresponded to age control.
在杂交小鼠中发现，对胸腺、下丘脑 - 垂体区域（两种情况均为0.5、1和10 Gy）以及性腺（10 Gy）进行局部照射，在照射后的长期内会导致体重显著增加。体重增加的动物体内脂质含量升高，激素平衡和免疫系统胸腺依赖单元的状态发生变化，并且观察到了早期衰老的外部症状。对脾脏和大腿肌肉进行照射（两种情况均为10 Gy）后，同期的所有指标与年龄对照组相符。
