Takada T, Uchiyama K, Yasuda H, Hasegawa H
First Department of Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Am J Surg. 1996 Jun;171(6):558-61. doi: 10.1016/s0002-9610(96)00041-4.
Choledochoscopic treatment has been used primarily to remove intrahepatic stones. However, failure in removing such stones can occasionally occur, resulting in the need for additional surgery. The aim of this study was to clarify the clinical indications and limitations of choledocoscopic treatment for the removal of intrahepatic stones.
A review of the records of 86 patients treated for intrahepatic stones between April 1974 and December 1993 formed the basis of this study. These patients were evaluated based on their bile-duct findings (no strictures, mild strictures, or severe strictures), the site of the stones (left hepatic lobe, right hepatic lobe, and the bilateral lobes), and the presence of variations in the posterior segmental bile-duct drainage.
Complete removal of stones was achieved in 59 patients (69%). Further, choledochoscopic removal was mainly successful in patients with no strictures or, to a lesser degree, with mild strictures; whereas stone removal was impossible in all patients (19) with severe strictures (P < 0.0001). As for the site of the stones, no statistical differences were seen among the three groups. Regarding the presence of drainage variations of the segmental bile duct, removal of the stones was more difficult in patients with variations than in those without variations (P < 0.01). With respect to long-term clinical outcomes, of the 59 successful patients, only 2 (3%) developed recurring stones.
Based on these findings, choledochoscopic treatment should be indicated for patients who have no, or only mild, bile-duct strictures and who mainifest normal segmental bile-duct drainage.
胆道镜治疗主要用于清除肝内结石。然而,偶尔会出现清除此类结石失败的情况,从而需要进行额外的手术。本研究的目的是阐明胆道镜治疗清除肝内结石的临床适应症和局限性。
回顾1974年4月至1993年12月期间86例接受肝内结石治疗患者的记录构成了本研究的基础。根据患者的胆管情况(无狭窄、轻度狭窄或重度狭窄)、结石部位(左肝叶、右肝叶和双侧肝叶)以及肝段胆管引流有无变异对这些患者进行评估。
59例患者(69%)实现了结石的完全清除。此外,胆道镜清除主要在无狭窄或轻度狭窄(程度较轻)的患者中成功;而在所有19例重度狭窄患者中结石清除均未成功(P<0.0001)。至于结石部位,三组之间未见统计学差异。关于肝段胆管引流变异的存在,有变异的患者比无变异的患者结石清除更困难(P<0.01)。关于长期临床结果,在59例成功患者中,只有2例(3%)出现复发性结石。
基于这些发现,胆道镜治疗适用于无胆管狭窄或仅有轻度胆管狭窄且肝段胆管引流正常的患者。