人体脂肪组织中硝基和非硝基苯系麝香化合物的存在情况。
Occurrence of nitro and non-nitro benzenoid musk compounds in human adipose tissue.
作者信息
Müller S, Schmid P, Schlatter C
机构信息
Institute of Toxicology, Swiss Federal Institute of Technology, Schwerzenbach, Switzerland.
出版信息
Chemosphere. 1996 Jul;33(1):17-28. doi: 10.1016/0045-6535(96)00160-9.
Nitro benzenoid musk compounds (Musk tibetene [CAS no. 145-39-1], Musk ambrette [83-66-9], Musk moskene [116-66-5], Musk ketone [81-14-1] and Musk xylene [81-15-2]) and non-nitro benzenoid musks (Celestolide [13171-00-1], Galaxolide [1222-05-5]) and Fixolide [1506-02-1] [21445-77-7] were analysed in 15 human adipose tissue samples from Switzerland by gas chromatography/high resolution mass spectrometry. The levels of Musk xylene and Galaxolide ranged up to 288 ng/g lipids and 171 ng/g lipids, respectively. The concentrations of non-nitro benzenoid musks found in human adipose tissue raise concern since very few toxicological data are available.
采用气相色谱/高分辨率质谱法对来自瑞士的15份人体脂肪组织样本中的硝基苯类麝香化合物（西藏麝香[CAS编号145 - 39 - 1]、葵子麝香[83 - 66 - 9]、麝香酮[116 - 66 - 5]、酮麝香[81 - 14 - 1]和二甲苯麝香[81 - 15 - 2]）、非硝基苯类麝香（佳乐麝香[13171 - 00 - 1]、 galaxolide [1222 - 05 - 5]）以及馥奇醇[1506 - 02 - 1][21445 - 77 - 7]进行了分析。二甲苯麝香和galaxolide的含量分别高达288纳克/克脂质和171纳克/克脂质。鉴于关于非硝基苯类麝香在人体脂肪组织中的毒理学数据非常有限，其在人体脂肪组织中的浓度令人担忧。
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