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IclR阻遏蛋白的结合位点与aceBAK的启动子重叠。

The binding site of the IclR repressor protein overlaps the promoter of aceBAK.

作者信息

Pan B, Unnikrishnan I, LaPorte D C

机构信息

Department of Biochemistry, University of Minnesota, Minneapolis, Minnesota 55455, USA.

出版信息

J Bacteriol. 1996 Jul;178(13):3982-4. doi: 10.1128/jb.178.13.3982-3984.1996.

DOI:10.1128/jb.178.13.3982-3984.1996
PMID:8682810
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC232666/
Abstract

In Escherichia coli, repression of the aceBAK operon is mediated by the IclR protein. We used an in vitro oligonucleotide selection technique to determine the consensus recognition sequence for MR. Mutational analysis confirmed the contribution of this sequence to repression in vivo and identified the -35 element of the promoter.

摘要

在大肠杆菌中，aceBAK操纵子的阻遏作用由IclR蛋白介导。我们使用体外寡核苷酸筛选技术来确定IclR的共有识别序列。突变分析证实了该序列在体内对阻遏作用的贡献，并确定了启动子的-35元件。

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本文引用的文献

1
Integration host factor amplifies the induction of the aceBAK operon of Escherichia coli by relieving IclR repression.整合宿主因子通过解除IclR的抑制作用来增强大肠杆菌aceBAK操纵子的诱导。
J Bacteriol. 1996 May;178(9):2715-7. doi: 10.1128/jb.178.9.2715-2717.1996.
2
Autoregulation of iclR, the gene encoding the repressor of the glyoxylate bypass operon.乙醛酸旁路操纵子阻遏物编码基因iclR的自动调节。
J Bacteriol. 1996 Jan;178(1):321-4. doi: 10.1128/jb.178.1.321-324.1996.
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Genetic regulation of the glyoxylate shunt in Escherichia coli K-12.大肠杆菌K-12中乙醛酸循环支路的遗传调控
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Bull Soc Chim Biol (Paris). 1967 Dec 18;49(11):1479-90.
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Culture medium for enterobacteria.用于肠道细菌的培养基。
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