Smith A J, Eggers K A, Stacey M R
Department of Anaesthesia, University Hospital of Wales, Cardiff.
Anaesthesia. 1996 May;51(5):495-7. doi: 10.1111/j.1365-2044.1996.tb07801.x.
The analgesic effect of topical ibuprofen was investigated in ten volunteers. There were no significant differences in visual analogue scale pain scores for pinprick after 15 and 60 min of application of ibuprofen, placebo and EMLA cream. Comparison of visual analogue scale scores for venous cannulation after similar durations of ibuprofen and EMLA creams found significantly (p < 0.014) lower scores for EMLA at 60 min. We do not consider ibuprofen cream to be clinically useful for venous cannulation.
在10名志愿者中研究了局部应用布洛芬的镇痛效果。在应用布洛芬、安慰剂和EMLA乳膏15分钟和60分钟后，针刺的视觉模拟评分疼痛分数没有显著差异。在布洛芬和EMLA乳膏应用相似时长后，对静脉穿刺的视觉模拟评分进行比较，发现60分钟时EMLA的评分显著更低（p < 0.014）。我们认为布洛芬乳膏对静脉穿刺在临床上并无用处。
