七氟烷和氟烷在儿童中的恢复特性比较。

A comparison of the recovery characteristics of sevoflurane and halothane in children.

作者信息

Sury M R, Black A, Hemington L, Howard R, Hatch D J, Mackersie A

机构信息

Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust, London.

出版信息

Anaesthesia. 1996 Jun;51(6):543-6. doi: 10.1111/j.1365-2044.1996.tb12560.x.

DOI:10.1111/j.1365-2044.1996.tb12560.x

PMID:8694205

Abstract

The recovery characteristics of sevoflurane and halothane anaesthesia were compared in 40 children aged 6 months to 6 years undergoing day case surgery. The mean time taken to open eyes after surgery had ended was appreciably and significantly shorter after sevoflurane than after halothane (sevoflurane, mean time (SD) 7 min 52 s (5 min 46 s), halothane, mean time (SD) 15 min 50 s (9 min 2 s), t = 3.32, p = 0.002). The time taken to be ready for discharge from the recovery unit to the ward was also significantly shorter after sevoflurane than after halothane (sevoflurane, mean time (SD) 12 min 46 s (4 min 11 s), halothane, mean time (SD) 19 min 13 s (9 min 48 s), t = 2.7, p < 0.01). However, more children were in pain and given analgesia after sevoflurane (p < 0.01) and the mean time to reach the criteria for discharge home was similar in both groups (sevoflurane, mean time (SD) 2 h 9 min (17 min), halothane, mean time (SD) 2 h 4 min (8 min)). There were no major complications in either group.

摘要

对40名年龄在6个月至6岁接受日间手术的儿童，比较了七氟烷和氟烷麻醉后的恢复特征。手术结束后，七氟烷组睁眼的平均时间明显且显著短于氟烷组（七氟烷，平均时间（标准差）7分52秒（5分46秒）；氟烷，平均时间（标准差）15分50秒（9分2秒），t = 3.32，p = 0.002）。从恢复室准备出院到病房的时间，七氟烷组也显著短于氟烷组（七氟烷，平均时间（标准差）12分46秒（4分11秒）；氟烷，平均时间（标准差）19分13秒（9分48秒），t = 2.7，p < 0.01）。然而，七氟烷麻醉后更多儿童出现疼痛并接受了镇痛治疗（p < 0.01），两组达到出院回家标准的平均时间相似（七氟烷，平均时间（标准差）2小时9分钟（17分钟）；氟烷，平均时间（标准差）2小时4分钟（8分钟））。两组均未出现重大并发症。