Bowman R, Liu C, Sarkies N
Department of Ophthalmology, Addenbrooke's Hospital, Cambridge.
Br J Ophthalmol. 1996 May;80(5):394-7. doi: 10.1136/bjo.80.5.394.
Two prospective studies were carried out in order to investigate (1) the rise in intraocular pressure (IOP) following peribulbar anaesthesia with a fixed volume of anaesthetic agent administered by a single surgeon, and (2) the efficacy of ocular compression with the Honan balloon for lowering IOP. Glaucomatous eyes were excluded from both studies.
In study group 1, 36 eyes of 36 patients undergoing cataract and/or implant surgery each received peribulbar injections consisting of 5 ml of anaesthetic from an inferotemporal site through the conjunctiva and a further 5 ml from a medial injection through the caruncle. IOP values were measured immediately before and after the injections and then after a variable period of external ocular compression. In study group 2, 20 eyes of 20 patients undergoing cataract surgery received peribulbar injections of local anaesthetic as above. IOP values were measured immediately before and after the injections and after 20 minutes without ocular compression. After a further 20 minute period with ocular compression the IOP was again measured.
In study group 1, the mean immediate rise in IOP induced by the injections was 11.44 (95% confidence interval 8.97-13.90) mm Hg. The mean change in IOP after ocular compression was an overall fall of 2.42 (0.49-4.34) mm Hg from the pre-injection value. In study group 2, the mean injection induced rise in IOP was 9.45 (6.90-12.00) mm Hg. The mean fall in IOP during the first 20 minutes without ocular compression was 2.85 (1.20-4.50) mm Hg. During the second 20 minutes with ocular compression the mean fall in intraocular pressure was 11.05 (8.14-14.96) mm Hg.
There is a large and individually variable rise in IOP following peribulbar anaesthesia. Ocular compression with the Honan balloon is effective in reversing this rise even when the initial rise is large.
开展两项前瞻性研究,以调查:(1)由同一位外科医生使用固定体积的麻醉剂进行球周麻醉后眼压(IOP)的升高情况;(2)使用霍南球囊进行眼部压迫降低眼压的效果。两项研究均排除青光眼患者。
在研究组1中,36例接受白内障和/或植入手术患者的36只眼均接受球周注射,从颞下部位经结膜注射5毫升麻醉剂,再从内眦经泪阜注射5毫升。在注射前、注射后以及在不同时间段的眼外压迫后测量眼压值。在研究组2中,20例接受白内障手术患者的20只眼接受上述局部麻醉剂的球周注射。在注射前、注射后以及无眼部压迫20分钟后测量眼压值。在进一步进行20分钟眼部压迫后再次测量眼压。
在研究组1中,注射引起的眼压平均即刻升高为11.44(95%置信区间8.97 - 13.90)毫米汞柱。眼部压迫后眼压的平均变化是较注射前值总体下降2.42(0.49 - 4.34)毫米汞柱。在研究组2中,注射引起的眼压平均升高为9.45(6.90 - 12.00)毫米汞柱。在无眼部压迫的前20分钟眼压平均下降2.85(1.20 - 4.50)毫米汞柱。在进行20分钟眼部压迫的第二个20分钟期间,眼压平均下降11.05(8.14 - 14.96)毫米汞柱。
球周麻醉后眼压会大幅升高且个体差异较大。即使初始眼压升高幅度较大,使用霍南球囊进行眼部压迫也能有效逆转这种升高。