The JAK-STAT pathway: summary of initial studies and recent advances.
作者信息
Darnell J E
机构信息
Rockefeller University, New York, New York 10021, USA.
出版信息
Recent Prog Horm Res. 1996;51:391-403; discussion 403-4.
PMID:8701087
Abstract
Polypeptides redirect cells by causing immediate changes in gene transcription. A direct connection between polypeptide receptors on the cell surface and genes in the nucleus has been provided by the recognition of the JAK-STAT pathway. Results leading to our present understanding of this pathway are reviewed.
摘要
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