Coleman J C, Waugh M, Dayton R
Br J Vener Dis. 1977 Apr;53(2):132-4. doi: 10.1136/sti.53.2.132.
Sera from 600 male homosexual patients were tested for hepatitis B antigen (HBs Ag) and its antibody (HBs Ab). Thirty-one men (5-2%) were positive for HBs Ag. Testing for HBs Ab by immuno-osmoelectrophoresis 33 men (5-5%) were positive. However, sera of 85 patients negative for HBs Ab by routine methods were examined for HBs Ab by radioimmune assay. Thirty (35%) sera were found to be positive. No absolute correlation between the detection of HBs Ag, or previous history of hepatitis, jaundice, or current hepatitis was found. Similarly there was little correlation between presence of HBs Ab and this history. These observations suggest that the male homosexual population represents a pool of individuals within which the hepatitis B virus is readily transmitted, mainly as a subclinical infection although clinical hepatitis does occur in some patients. It is suggested that further work is necessary to determine whether the high antibody rate in male homosexuals is related more to sexual practice than to promiscuity.
对600名男性同性恋患者的血清进行了乙肝抗原（HBs Ag）及其抗体（HBs Ab）检测。31名男性（5.2%）HBs Ag呈阳性。通过免疫渗透电泳检测HBs Ab，33名男性（5.5%）呈阳性。然而，对85例常规方法检测HBs Ab阴性患者的血清进行放射免疫分析检测HBs Ab。发现30例（35%）血清呈阳性。未发现HBs Ag检测结果、既往肝炎、黄疸病史或当前肝炎之间存在绝对相关性。同样，HBs Ab的存在与该病史之间也几乎没有相关性。这些观察结果表明，男性同性恋人群是乙肝病毒易于传播的个体群体，主要以亚临床感染形式传播，尽管某些患者确实会发生临床肝炎。建议有必要进一步开展工作，以确定男性同性恋者中高抗体率是否更多与性行为有关，而非与滥交有关。
