Lee K, Buhr J, Hausman G J, Wright T, Dean R
Department of Animal and Daity Science, University of Georgia, Athens 30602, USA.
Mol Cell Biochem. 1996 Feb 9;155(1):31-5. doi: 10.1007/BF00714330.
Subcutaneous adipose tissue from fetal pigs was examined for c-Fos expression in developing adipocytes. Enhanced c-Fos expression was found in the nuclei of adipocytes and cells closely associated with fat cell clusters from 75 and 105 day old fetuses. 50 day old fetuses which had no adipocytes showed no enhanced c-Fos expression in undifferentiated cells. c-Fos expression in adipocytes was not transient, but persisted through the gestational period from 75 to 105 days. The timing of c-Fos induction appears to be closely related to adipocyte differentiation and was found only in developing adipocytes and cells closely associated with fat cell cluster and was not found in independent stromal-vascular cells.
研究了来自胎猪的皮下脂肪组织中发育中的脂肪细胞的c-Fos表达情况。在75日龄和105日龄胎儿的脂肪细胞核以及与脂肪细胞簇紧密相关的细胞中发现c-Fos表达增强。没有脂肪细胞的50日龄胎儿在未分化细胞中未显示c-Fos表达增强。脂肪细胞中的c-Fos表达不是短暂的，而是在75至105天的妊娠期持续存在。c-Fos诱导的时间似乎与脂肪细胞分化密切相关，并且仅在发育中的脂肪细胞和与脂肪细胞簇紧密相关的细胞中发现，而在独立的基质血管细胞中未发现。
