Jahnukainen K, Pöllänen P, Giwercman A, Skakkebaek N E
University of Turku, Finland.
Int J Androl. 1995 Dec;18(6):313-20. doi: 10.1111/j.1365-2605.1995.tb00568.x.
The incidence of mononuclear cell (MNC) infiltrates was studied in the testes of the following: 45 patients with carcinoma in situ (CIS) as the only lesion in the testis, CIS accompanied by an early invasion of CIS or CIS accompanied by invasive germ cell tumour (GCT) of the testis; 100 men and 146 boys who had died suddenly and unexpectedly, and 100 infertility patients. The results suggest that (1) the incidence of MNC infiltration increases with increasing severity of testicular malignant changes, (2) increased MNC infiltration is also evident in the contralateral testis where no malignant cells can be observed, (3) the incidence of MNC infiltration in men who died suddenly is not different from that in men who have had their testes biopsied because of infertility, and (4) the incidence of MNC infiltration is high in testes of boys younger than 1 year of age.
对以下人群的睾丸中单核细胞（MNC）浸润发生率进行了研究：45例睾丸原位癌（CIS）患者，其睾丸中唯一病变为CIS；CIS伴有CIS早期浸润或CIS伴有睾丸浸润性生殖细胞肿瘤（GCT）；100名突然意外死亡的男性和146名男孩，以及100名不育症患者。结果表明：（1）MNC浸润发生率随睾丸恶性病变严重程度的增加而升高；（2）在对侧睾丸中，虽未观察到恶性细胞，但MNC浸润也明显增加；（3）突然死亡男性的MNC浸润发生率与因不育接受睾丸活检男性的发生率无差异；（4）1岁以下男孩的睾丸中MNC浸润发生率较高。
