细胞表面疏水性和脂肪分解作为人类黑癣的关键因素。

Cell-surface hydrophobicity and lipolysis as essential factors in human tinea nigra.

作者信息

Göttlich E, de Hoog G S, Yoshida S, Takeo K, Nishimura K, Miyaji M

机构信息

Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.

出版信息

Mycoses. 1995 Nov-Dec;38(11-12):489-94. doi: 10.1111/j.1439-0507.1995.tb00026.x.

DOI:10.1111/j.1439-0507.1995.tb00026.x

PMID:8720202

Abstract

Hydrophobic adhesion of cells of the black yeast Hortaea werneckii (Horta) Nishimura & Miyaji, causative agent of human tinea nigra, was established by microbial adhesion to hexadecane (MATH) and adhesion to polystyrene, and compared with adhesion of other species of black yeasts. Additional ecophysiological tests were performed. Hortaea werneckii cells proved to have a high degree of hydrophobicity (98.5% MATH). The species is unable to degrade keratin, but shows significant lipolytic activity. It is concluded that H. werneckii is a commensal, that shows lipophilic adhesion to human skin and survives by the assimilation of excretion products.

摘要

人类黑癣病原菌——黑色酵母菌渥氏霍塔酵母（Horta）西村 & 宫路的细胞通过微生物对十六烷的粘附（MATH）和对聚苯乙烯的粘附建立了疏水粘附，并与其他黑色酵母菌的粘附进行了比较。还进行了额外的生态生理学测试。结果证明，渥氏霍塔酵母细胞具有高度疏水性（MATH为98.5%）。该菌种无法降解角蛋白，但具有显著的脂解活性。得出的结论是，渥氏霍塔酵母是一种共生菌，对人类皮肤表现出亲脂性粘附，并通过同化排泄产物而存活。