Colonna M, Anastasi G P, Cavallaro G, Signorini M, Tomasello F
Department of Plastic Surgery, University of Messina Medical School, Milan, Italy.
J Reconstr Microsurg. 1996 May;12(4):205-10. doi: 10.1055/s-2007-1006477.
The role of autogenous vein grafts in nerve regeneration was studied in a rat model. Three groups of animals underwent autogenous vein grafting for ischiatic nerve regeneration, and were sacrificed 30, 60, and 90 days after surgery. Samples obtained were processed for S.E.M. study. Nerve regeneration consisted of two stages: the first (up to 60 days) was characterized by the presence of active endothelial cells; the second (after 60 days) by cell disappearance, with the venous wall acting as a protective conduit throughout both steps. Complete qualitative morphologic and functional studies of neural regeneration are presented, confirming previous investigations.
在大鼠模型中研究了自体静脉移植在神经再生中的作用。三组动物接受了自体静脉移植以促进坐骨神经再生，并在术后30天、60天和90天处死。所获得的样本进行处理以用于扫描电子显微镜（S.E.M.）研究。神经再生包括两个阶段：第一阶段（直至60天）的特征是存在活跃的内皮细胞；第二阶段（60天后）的特征是细胞消失，在这两个阶段中静脉壁均作为保护性管道。本文展示了对神经再生的完整定性形态学和功能研究，证实了先前的研究。
