Tielsch J M
Department of International Health, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland 21205, USA.
Annu Rev Public Health. 1996;17:121-36. doi: 10.1146/annurev.pu.17.050196.001005.
Chronic open angle glaucoma is an etiologically heterogeneous group of diseases characterized by damage to the optic nerve, resulting in peripheral visual loss that can progress to involve the fovea and central vision. Open angle glaucoma can be divided into primary conditions and conditions which are secondary to another ocular or systemic disease. Causes of secondary glaucoma include uveitis, cataract, trauma, and disorders affecting the development structure of the angle. This review focuses on primary open angle glaucoma (POAG), since it accounts for the vast majority of the disease burden in the US population and its etiology remains unknown.
慢性开角型青光眼是一组病因异质性疾病，其特征为视神经受损，导致周边视力丧失，并可能进展至累及黄斑和中心视力。开角型青光眼可分为原发性青光眼和继发于其他眼部或全身性疾病的青光眼。继发性青光眼的病因包括葡萄膜炎、白内障、外伤以及影响房角发育结构的疾病。本综述重点关注原发性开角型青光眼（POAG），因为它在美国人群的疾病负担中占绝大多数，且其病因尚不清楚。
