Department of Radiology, National Guard Hospital, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
J Epidemiol Glob Health. 2019 Sep;9(3):198-203. doi: 10.2991/jegh.k.190816.001.
To determine the prevalence of glaucoma in obstructive sleep apnea (OSA) patients and compare it with that of patients without OSA. Patients investigated for OSA using polysomnography at the sleep center of King Abdulaziz University Hospital were invited to participate in this cross-sectional case series study. American Academy of Sleep Medicine guidelines were used to diagnose OSA. Recruitment of patients with and without OSA was conducted from December 2013 to September 2015. Exclusion criteria included topical and systemic steroid use and presence of other ocular diseases. Two criteria, cup/disc ratio and visual field defects, were necessary for a glaucoma diagnosis. Among 84 adults enrolled, 44 (52%) had a confirmed diagnosis of OSA. Glaucoma prevalence was higher among individuals with OSA (16%) than among non-OSA individuals (8%), a difference that was not statistically significant. A consistent trend, which was not statistically significant after adjusting for cofounders, toward more glaucomatous changes was observed in OSA subjects. Although a trend toward higher glaucoma prevalence was observed in OSA patients, the difference was not statistically significant. As many variables contribute to the development of the two conditions, larger cohorts are needed to evaluate associations between glaucoma and OSA.
确定阻塞性睡眠呼吸暂停（OSA）患者中青光眼的患病率，并将其与无 OSA 患者进行比较。
邀请在阿卜杜勒阿齐兹国王大学医院睡眠中心接受多导睡眠图检查以诊断 OSA 的患者参与这项横断面病例系列研究。使用美国睡眠医学学会指南诊断 OSA。于 2013 年 12 月至 2015 年 9 月招募有和无 OSA 的患者。排除标准包括局部和全身皮质类固醇的使用以及存在其他眼部疾病。青光眼的诊断需要两个标准，即杯盘比和视野缺损。在纳入的 84 名成年人中，44 名（52%）确诊为 OSA。OSA 患者的青光眼患病率（16%）高于非 OSA 患者（8%），但差异无统计学意义。在调整混杂因素后，观察到 OSA 患者的青光眼变化趋势更为明显，但差异无统计学意义。尽管在 OSA 患者中观察到青光眼患病率升高的趋势，但差异无统计学意义。由于许多变量都会导致这两种疾病的发生，因此需要更大的队列来评估青光眼和 OSA 之间的关联。
