Haffter P, Nüsslein-Volhard C
Max-Planck-Institut für Entwicklungsbiologie, Tübingen, Germany.
Int J Dev Biol. 1996 Feb;40(1):221-7.
The systematic isolation and characterization of mutants in Drosophila has enormously facilitated the analysis of molecular mechanisms underlying developmental pathways in the embryo. A similar approach is presently being used to study embryonic development of the zebrafish, which is becoming a mainstream model organism for vertebrate development. With its genetic versatility and sophisticated embryology, zebrafish offers the possibility to rapidly increase our knowledge of vertebrate development and add to what we have learned from other vertebrate model organisms.
在果蝇中对突变体进行系统的分离和特性分析极大地推动了对胚胎发育途径潜在分子机制的研究。目前，类似的方法正被用于研究斑马鱼的胚胎发育，斑马鱼正成为脊椎动物发育研究的主流模式生物。凭借其遗传多样性和复杂的胚胎学，斑马鱼为快速增加我们对脊椎动物发育的了解并补充我们从其他脊椎动物模式生物中学到的知识提供了可能性。
