葡萄球菌中的溶菌活性。
Bacteriolytic activity in staphylococci.
作者信息
Satta G, Varaldo P E, Grazi G, Fontana R
出版信息
Infect Immun. 1977 Apr;16(1):37-42. doi: 10.1128/iai.16.1.37-42.1977.
The bacteriolytic activity of Staphylococcus aureus and Staphylococcus albus strains was tested with various media. Whereas S. aureus strains were found to be active under all conditions, the percentage of active S. albus strains was significantly influenced by the composition of the medium. Ionic strength and concentration of the organic nitrogen source were found to be the main factors affecting the expression of bacteriolytic activity of straphylococci. Virtually all of 318 S. aureus and 603 S. albus strains were active on a medium containing 3% peptone, 0.3% glucose, 0.2% yeast extract, 0.1% disodium phosphate, 2.2% sodium chloride and 0.9% agar. The optimal conditions for the bacteriolytic activity of S. aureus strains were different from those of most S. albus strains. Within S. albus, optimal conditions differed also from strain to strain. It is suggested that further studies on this subject may prove useful for the identification and taxonomy of staphylococci. A possible relationship between the production of extracellular bacteriolytic enzymes and pathogenic properties of staphylococci is also considered.
用各种培养基测试了金黄色葡萄球菌和白色葡萄球菌菌株的溶菌活性。虽然发现金黄色葡萄球菌菌株在所有条件下均有活性，但白色葡萄球菌活性菌株的百分比受培养基成分的显著影响。发现离子强度和有机氮源浓度是影响葡萄球菌溶菌活性表达的主要因素。实际上，318株金黄色葡萄球菌和603株白色葡萄球菌在含有3%蛋白胨、0.3%葡萄糖、0.2%酵母提取物、0.1%磷酸氢二钠、2.2%氯化钠和0.9%琼脂的培养基上均有活性。金黄色葡萄球菌菌株溶菌活性的最佳条件与大多数白色葡萄球菌菌株不同。在白色葡萄球菌中，不同菌株的最佳条件也有所不同。建议对该主题进行进一步研究可能对葡萄球菌的鉴定和分类有用。还考虑了细胞外溶菌酶的产生与葡萄球菌致病特性之间的可能关系。
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