醋氯芬酸与双氯芬酸抗炎作用及胃肠道耐受性的比较。
Comparison of the anti-inflammatory effect and gastrointestinal tolerability of aceclofenac and diclofenac.
作者信息
Arañó A, Zapatero M I, Basi N, Duque A, Gropper S
机构信息
Centro de Investigación y Desarrollo Aplicado, S.A.L., Barcelona, Spain.
出版信息
Arzneimittelforschung. 1996 Apr;46(4):398-400.
PMID:8740087
Abstract
Aceclofenac (CAS 89796-99-6) and diclofenac (CAS 15307-79-6) are orally effective non-steroidal anti-inflammatory drugs. Their anti-inflammatory and potential gastrointestinal damaging effects were compared following single and repeated administration (5 days). Both drugs exerted an anti-inflammatory activity and showed a similar gastrointestinal tolerability in the rat.
摘要
醋氯芬酸（CAS 89796-99-6）和双氯芬酸（CAS 15307-79-6）是口服有效的非甾体抗炎药。在单次和重复给药（5天）后，对它们的抗炎作用和潜在的胃肠道损伤作用进行了比较。两种药物均具有抗炎活性，并且在大鼠中显示出相似的胃肠道耐受性。
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