Syvälahti E, Pekkarinen A
J Neural Transm. 1977;40(3):221-6. doi: 10.1007/BF01300136.
Ten schizophrenic and five epileptic patients under antipsychotic drug treatment were studied to evaluate sleep-related GH secretion. Four of the schizophrenic patients had a high secretion peak of GH (range 15.2 to 38.0 ng/ml), four had a moderate peak (range 5.8--8.3 ng/ml), while two had no increase in GH secretion during sleep (range 0.5--1.0 ng/mg). Four of the five epileptic patients had a moderately increased secretion (range 5.8--9.2 ng/ml) and one had no increase in GH secretion during sleep. Thus, the GH secretory pattern varied with the patient as in known to be also with healthy individuals. However, no clear disturbances were noted in sleep-related GH secretion in schizophrenic patients receiving antipsychotic drug treatment, when compared e.g. to non-schizophrenic, epileptic patients under a same kind of drug treatment.
对10名接受抗精神病药物治疗的精神分裂症患者和5名癫痫患者进行了研究，以评估与睡眠相关的生长激素（GH）分泌情况。10名精神分裂症患者中，4人GH分泌峰值较高（范围为15.2至38.0 ng/ml），4人峰值中等（范围为5.8 - 8.3 ng/ml），而2人在睡眠期间GH分泌未增加（范围为0.5 - 1.0 ng/mg）。5名癫痫患者中，4人分泌适度增加（范围为5.8 - 9.2 ng/ml），1人在睡眠期间GH分泌未增加。因此，GH分泌模式因患者而异，已知健康个体也是如此。然而，与例如接受相同药物治疗的非精神分裂症癫痫患者相比，接受抗精神病药物治疗的精神分裂症患者在与睡眠相关的GH分泌方面未发现明显紊乱。
