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[咽鼓管黏膜分泌细胞及表面活性物质样板层小体的超微细胞化学观察]

[Ultracytochemical observation of secretory cells and surfactant-like lamellar bodies in mucosa of eustachian tube].

作者信息

Yang W, Wang R, Sun J

机构信息

PLA General Hospital, Beijing.

出版信息

Zhonghua Er Bi Yan Hou Ke Za Zhi. 1995;30(4):224-6.

PMID:8745462
Abstract

The distribution of secretory cells and surfactant-like lamellar bodies in mucosa of the guinea pig eustachian tube were studied ultracytochemically. Classified by means of their morphologic characteristics, three types of secretory cells were identified. The dark granulated cells were predominant in the tympanic orifice, the mixed cells were predominant in the isthmus portion, while the light cells were predominant in the pharyngeal orifice. The distribution of the secretory cells in different part of the eustachian tube might play a role in the pathogenesis of middle ear effusions. Surfactant-like lamellar bodies were found in ciliated cells, nonciliated cells and secretory cells of the eustachian tube mucosa. Surfactant-like lamellar bodies (surfactant-like substance) are important in maintaining the physiological function of the eustachian tube, their behavior in normal and pathological states should be further studied.

摘要

采用超微细胞化学方法研究了豚鼠咽鼓管黏膜中分泌细胞和表面活性剂样板层小体的分布。根据形态学特征分类,鉴定出三种类型的分泌细胞。暗颗粒细胞在鼓室口占优势,混合细胞在峡部占优势,而亮细胞在咽口占优势。咽鼓管不同部位分泌细胞的分布可能在中耳积液的发病机制中起作用。在咽鼓管黏膜的纤毛细胞、无纤毛细胞和分泌细胞中发现了表面活性剂样板层小体。表面活性剂样板层小体(表面活性剂样物质)对维持咽鼓管的生理功能很重要,其在正常和病理状态下的行为有待进一步研究。

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