Bonnet M H, Arand D L
Dayton Veterans Affairs Medical Center, Wright State University, Ohio, USA.
Sleep. 1995 Dec;18(10):908-11. doi: 10.1093/sleep/18.10.908.
Data from recent laboratory studies indicate that nocturnal sleep periods reduced by as little as 1.3 to 1.5 hours for 1 night result in reduction of daytime alertness by as much as 32% as measured by the Multiple Sleep Latency Test (MSLT). Other data document that 1) 17%-57% of normal young adults have MSLT latencies of < or = 5.5 minutes, whereas < or = 50% have MSLT values of > or = 10 minutes and 2) 28%-29% of young adults reported normally sleeping < or = 6.5 hours on each weeknight. More extensive reduction of daily sleep amount is seen in nightshift workers. A minimum of 2%-4% of middle-aged adults have hypersomnolence associated with sleep apnea. Together, these data show that significant sleep loss exists in one-third or more of normal adults, that the effects are large and replicable and that similar effects can be produced in just 1 night in the laboratory. In light of the magnitude of this sleep debt, it is not surprising that fatigue is a factor in 57% of accidents leading to the death of a truck driver and in 10% of fatal car accidents and results in costs of up to 56 billion dollars per year. A recent sleep extension study suggests that the average underlying sleep tendency in young adults is about 8.5 hours per night. By comparison, the average reported sleep length of 7.2-7.4 hours is deficient, and common sleep lengths of < or = 6.5 hours can be disastrous. We must recognize the alertness function of sleep and the increasing consequences of sleepiness with the same vigor that we have come to recognize the societal impact of alcohol.
近期实验室研究数据表明,夜间睡眠时间仅减少1.3至1.5小时,持续1晚,通过多次睡眠潜伏期试验(MSLT)测量,白天警觉性会降低多达32%。其他数据表明:1)17%-57%的正常年轻成年人MSLT潜伏期小于或等于5.5分钟,而小于或等于50%的人MSLT值大于或等于10分钟;2)28%-29%的年轻成年人报告称,他们平时每个工作日夜晚睡眠时间小于或等于6.5小时。夜班工作者每日睡眠量减少得更多。至少2%-4%的中年成年人患有与睡眠呼吸暂停相关的嗜睡症。这些数据共同表明,三分之一或更多的正常成年人存在严重睡眠不足,其影响巨大且可重复,在实验室仅1晚就能产生类似影响。鉴于这种睡眠债的规模,疲劳成为57%导致卡车司机死亡的事故以及10%致命汽车事故的一个因素,并每年造成高达560亿美元的损失,也就不足为奇了。最近一项睡眠延长研究表明,年轻成年人的平均潜在睡眠倾向约为每晚8.5小时。相比之下,报告的平均睡眠时间7.2 - 7.4小时是不足的,常见的小于或等于6.5小时的睡眠时间可能是灾难性的。我们必须像认识到酒精对社会的影响那样,同样积极地认识到睡眠的警觉功能以及困倦日益增加的后果。