Jordan S C, Ament M E
J Pediatr. 1977 Aug;91(2):211-6. doi: 10.1016/s0022-3476(77)80814-7.
Normal serum amylase values were established for the pediatric age group (47.7 +/- 28.6 mg/dl); these are higher than previously stated. Average serum amylase values increased with increasing age (r = 0.55). The three commonest causes of pancreatitis in 54 patients studied were drug induced (16), idiopathic (10), and traumatic (7). Prednisone was the most frequently implicated drug. Midepigastric pain and vomiting were the presenting symptoms in 75% of the patients. Serum amylase values were more than three times normal in 63.8% of patients; 17% of patients presented with normal serum amylase values. The typical patient received intravenous therapy for 5.4 days and was hospitalized for 9.4 days. Treatment with antibiotic and anticholinergic drugs did not alter mortality or morbidity rates. Mortality rate for acute interstitial pancreatitis was 17.5%, and for acute hemorrhagic pancreatitis was 86%.
确定了儿科年龄组的正常血清淀粉酶值（47.7±28.6毫克/分升）；这些值高于先前报道的数值。血清淀粉酶平均值随年龄增长而升高（r = 0.55）。在研究的54例患者中，胰腺炎最常见的三个病因是药物性（16例）、特发性（10例）和外伤性（7例）。泼尼松是最常涉及的药物。中上腹疼痛和呕吐是75%患者的首发症状。63.8%患者的血清淀粉酶值超过正常上限的三倍；17%患者的血清淀粉酶值正常。典型患者接受了5.4天的静脉治疗，住院9.4天。使用抗生素和抗胆碱能药物治疗并未改变死亡率或发病率。急性间质性胰腺炎的死亡率为17.5%，急性出血性胰腺炎的死亡率为86%。
