Gadian D G
Radiology and Physics Unit, Institute of Child Health, London, UK.
Magn Reson Imaging. 1995;13(8):1193-5. doi: 10.1016/0730-725x(95)02032-o.
Proton magnetic resonance spectra include signals from N-acetylaspartate, creatine + phosphocreatine, and choline-containing compounds. Abnormalities in these signals can be used in the assessment of patients with intractable epilepsy. In particular, they provide a means of identifying metabolic abnormalities within the temporal lobes, detecting bilateral and diffuse pathology, and aiding lateralization of the seizure focus. The pathology demonstrated on MRS can also be related to cognitive dysfunction.
质子磁共振波谱包括来自N-乙酰天门冬氨酸、肌酸+磷酸肌酸以及含胆碱化合物的信号。这些信号的异常可用于评估难治性癫痫患者。特别是，它们提供了一种识别颞叶内代谢异常、检测双侧和弥漫性病变以及辅助癫痫发作灶定位的方法。磁共振波谱显示的病变也可能与认知功能障碍有关。
