Guo J J, Gibson J T, Hancock G R, Barker K N
Department of Pharmacy Care Systems, Auburn University School of Pharmacy, Alabama, USA.
Clin Ther. 1995 Nov-Dec;17(6):1174-87. doi: 10.1016/0149-2918(95)80096-4.
The objectives of this study were to evaluate the effectiveness of drug utilization review (DUR) letter intervention on reducing the cost of medications under Medicaid. The target drugs in this study were six antiulcer agents prescribed for Alabama Medicaid recipients. The study group consisted of 100 prescribers who received DUR intervention. A total of 3776 prescribers who did not receive DUR intervention served as the comparison group. Using an interrupted time series design, these 3876 prescribers were studied before and after the implementation of the DUR program. The study found that prescribers' behavior changed after the DUR letter were sent out, resulting in a reduction in the average marginal days of drug therapy and drug reimbursement per recipient. For the target drugs, there was an average savings of $112.73 per prescriber per month and a total of $136,370.82 savings per month for the Alabama Medicaid program.
本研究的目的是评估药物利用审查（DUR）信函干预对降低医疗补助计划下药物成本的有效性。本研究中的目标药物是为阿拉巴马州医疗补助计划受益人群开具的六种抗溃疡药物。研究组由100名接受DUR干预的开处方者组成。共有3776名未接受DUR干预的开处方者作为对照组。采用间断时间序列设计，对这3876名开处方者在DUR计划实施前后进行了研究。研究发现，在发出DUR信函后，开处方者的行为发生了变化，导致每位受益人的平均药物治疗边际天数和药物报销减少。对于目标药物，每位开处方者每月平均节省112.73美元，阿拉巴马州医疗补助计划每月总共节省136370.82美元。
