Bagyan I, Hobot J, Cutting S
Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia 19104-6076, USA.
J Bacteriol. 1996 Aug;178(15):4500-7. doi: 10.1128/jb.178.15.4500-4507.1996.
We have identified a new Bacillus subtilis gene, spoVT, whose gene product is homologous to the transcriptional regulator AbrB and serves as a regulator of E sigmaG-controlled gene expression. SpoVT acts both positively and negatively in controlling sigmaG-dependent gene expression, providing an additional level of refinement to forespore gene regulation and feedback control of spoIIIG expression.
我们鉴定出一个新的枯草芽孢杆菌基因spoVT,其基因产物与转录调节因子AbrB同源,并作为E sigmaG控制的基因表达的调节因子。SpoVT在控制sigmaG依赖性基因表达中既起正向作用也起负向作用,为前芽孢基因调控和spoIIIG表达的反馈控制提供了额外的精细调控水平。