Wecker I
Med Microbiol Immunol. 1977 May 18;163(1):45-51. doi: 10.1007/BF02126708.
Between early July and August 1976, 60 cases of aseptic meningitis and pharyngitis in children from various parts of West Germany were reported to this institute. Successful virus isolation from spinal fluid in 12 out of 36 cases was greatly facilitated by the use of RD cell tissue cultures, whereas isolation attempts in HEL, Vero, and HFDK cells were unsuccessful. In all cases, the isolated virus was identified as ECHO type 30. Neutralization studies with sera of 48 remaining cases also using RD cells clearly indicated that the epidemic outbreak was caused by ECHO type 30 virus.
1976年7月初至8月期间，西德各地向本研究所报告了60例儿童无菌性脑膜炎和咽炎病例。在36例病例中，有12例通过使用RD细胞组织培养成功从脑脊液中分离出病毒，而在HEL、Vero和HFDK细胞中进行的分离尝试均未成功。在所有病例中，分离出的病毒被鉴定为埃可30型。对其余48例病例的血清也使用RD细胞进行的中和研究清楚地表明，此次疫情爆发是由埃可30型病毒引起的。
