与水痘-带状疱疹病毒基因21同源的猿猴水痘病毒（SVV）在被SVV潜伏感染的猴神经节中表达。
A simian varicella virus (SVV) homolog to varicella-zoster virus gene 21 is expressed in monkey ganglia latently infected with SVV.
作者信息
Clarke P, Matlock W L, Beer T, Gilden D H
机构信息
Department of Neurology, University of Colorado Health Sciences Center, Denver 80262, USA.
出版信息
J Virol. 1996 Aug;70(8):5711-5. doi: 10.1128/JVI.70.8.5711-5715.1996.
Abstract
We have sequenced a simian varicella virus (SVV) open reading frame (ORF), 3,123 bp in length, whose product has 51% amino acid homology with the sequence encoded by the ORF of varicella-zoster virus gene 21. Several regions are highly conserved between the two ORFs, with homologies of approximately 80%. The SVV gene is transcribed in tissue culture cells productively infected with SVV and in monkey ganglia latently infected with SVV.
摘要
我们对一个长度为3123 bp的猴水痘病毒（SVV）开放阅读框（ORF）进行了测序，其产物与水痘-带状疱疹病毒基因21的ORF编码序列具有51%的氨基酸同源性。两个ORF之间的几个区域高度保守，同源性约为80%。SVV基因在被SVV有效感染的组织培养细胞以及被SVV潜伏感染的猴神经节中进行转录。
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