Sittek H, Kessler M, Heuck A F, Lebeau A, Kohnert M, Untch M, Bohmert H, Reiser M
Institut für Radiologische Diagnostik, Klinikum Grosshadern, Ludwig-Maximilians-Universität, München.
Rofo. 1996 Jul;165(1):59-63. doi: 10.1055/s-2007-1015714.
The capacity of dynamic contrast-enhanced MR mammography to distinguish between different forms and grades of mastopathy according to Prechtel's classification was evaluated in a retrospective study.
MR mammograms of 51 patients with histologically proven mastopathy were retrospectively evaluated in areas subsequently biopsied.
Mean values of regressive and hyperplastic types of mastopathy differed significantly no significant differences were found between proliferating and non-proliferating mastopathies or Prechtel grades I-III mastopathy when MRI data obtained with a FLASH 3 D sequence (TR = 8.4 ms, TE = 3 ms, flip angle = 30 degrees at 1.0 T) were compared one minute, three, 5 and 8 minutes after i.v. bolus administration of contrast media (Gd-DTPA, 0.1 mmol/kg body weight).
Our data indicate that dynamic contrast-enhanced MR mammography does not allow the differentiation of proliferating and non-proliferating mastopathy according to the Prechtel classification. Dynamic MR mammography assessment of breast cancer risk does not seem to be feasible.
