Erenmemisoglu A, Ustun H, Kartal M
Department of Pharmacology, Medical Faculty, Erciyes University, Kayseri, Turkey.
Cytopathology. 1995 Dec;6(6):403-8. doi: 10.1111/j.1365-2303.1995.tb00487.x.
A type of smokeless tobacco, known as Maras powder, is widely used in lieu of cigarettes in the south-eastern region of Turkey. In the present study, we evaluated cytological smears obtained from the lesion of lower lip mucosa of 80 smokeless tobacco users. There were severe epithelial abnormalities in seven out of the 80 subjects. Punch biopsies from these cases disclosed dysplasia in three cases, carcinoma in situ in two, and carcinoma in the other two cases. There was mild dysplasia in two punch biopsies of the remaining 73 cases. Oral cancer in tobacco powder users appeared to be related to the length of use, as it was observed only in subjects with 15 or more years of exposure.
一种名为马拉斯粉的无烟烟草在土耳其东南部被广泛用于替代香烟。在本研究中，我们评估了80名无烟烟草使用者下唇黏膜病变处获取的细胞学涂片。80名受试者中有7名存在严重上皮异常。对这些病例进行的切取活检显示，3例为发育异常，2例为原位癌，另外2例为癌。其余73例中的2例切取活检显示轻度发育异常。烟草粉使用者的口腔癌似乎与使用时长有关，因为仅在暴露15年或更长时间的受试者中观察到。
