Louis E D, Marder K, Cote L, Wilder D, Tang M X, Lantigua R, Gurland B, Mayeux R
Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, New York, USA.
Mov Disord. 1996 Jan;11(1):63-9. doi: 10.1002/mds.870110112.
The purpose of this study was to determine the prevalence and functional and diagnostic correlates of reported shaking in the community-dwelling elderly. We conducted a standardized neurological evaluation of 1,056 nondemented Medicare recipients in Washington Heights-Inwood, Northern Manhattan (New York). Of 1,056 patients, 108 reported shaking (10.2%). The prevalence of reported shaking did not increase with age. It did differ between ethnic groups, but when adjusted for depression and score on the Schwab and England Activities of Daily Living (ADL) scale, this difference was insignificant. The age-adjusted prevalence was similar for women and men. Neurological examination of the 108 who reported shaking showed that 8.3% had tremor at rest, 17.6% had tremor with action, 5.6% had dyskinesia or chorea, and an additional 28.7% had various problems in coordination or movement. The remaining 39.8% had neither tremor nor problems in coordination or movement. Only 2.9% of individuals with reported shaking had Parkinson's disease (PD), 8.7% had essential tremor, and 2.1% had oral-buccal-lingual dyskinesia. Of the remaining 86.3%, 29 (31%) had no identifiable medical condition. Those who reported shaking were less independent with ADLs, regardless of presence of tremor on examination. Shaking is commonly reported by the community-dwelling elderly. It does not necessarily identify individuals with essential tremor and PD, and is related to decreased independence in ADLs.
本研究的目的是确定社区居住老年人中报告的震颤的患病率及其功能和诊断相关性。我们对纽约曼哈顿北部华盛顿高地-因伍德的1056名非痴呆医疗保险受益人进行了标准化神经学评估。在1056名患者中，108人报告有震颤（10.2%）。报告的震颤患病率并未随年龄增长而增加。不同种族之间存在差异，但在对抑郁以及施瓦布和英格兰日常生活活动（ADL）量表得分进行校正后，这种差异并不显著。经年龄校正后的患病率在女性和男性中相似。对报告有震颤的108人进行神经学检查发现，8.3%的人有静止性震颤，17.6%的人有动作性震颤，5.6%的人有运动障碍或舞蹈症，另外28.7%的人在协调或运动方面存在各种问题。其余39.8%的人既没有震颤，也没有协调或运动方面的问题。报告有震颤的个体中只有2.9%患有帕金森病（PD），8.7%患有特发性震颤，2.1%患有口颊舌运动障碍。在其余86.3%的人中，29人（31%）没有可识别的医学病症。报告有震颤的人在日常生活活动方面独立性较差，无论检查时是否存在震颤。社区居住老年人中普遍报告有震颤。震颤不一定能识别出患有特发性震颤和帕金森病的个体，并且与日常生活活动独立性下降有关。
