Nasonov E L, Karpov Iu A, Alekberova Z S, Vil'chinskaia M Iu, Fomicheva O A, Aleksandrova E N, Reshetniak T M, Kliukvina N G, Andreev A Ia
Ter Arkh. 1996;68(2):37-40.
Antiphospholipid syndrome (APLS) is defined as a symptom complex characterized by arterial and venous thromboses, obstetric abnormalities, thrombocytopenia and hyperproduction of antiphospholipid antibodies. APLS may be primary and secondary developing in the presence of autoimmune disorders, SLE in particular. At examination of 28 patients with primary and secondary APLS 14 patients proved hypertensive. Renal pathology was absent. Arterial hypertension appeared often in combination with microthrombi of the skin and affections of peripheral vessels. Arterial hypertension as a cardiological sign of APLS occurs more frequently than other symptoms.
抗磷脂综合征(APLS)被定义为一种以动静脉血栓形成、产科异常、血小板减少和抗磷脂抗体过度产生为特征的症状复合体。APLS可能是原发性的,也可能是在自身免疫性疾病(尤其是系统性红斑狼疮)存在的情况下继发性发展而来。在对28例原发性和继发性APLS患者进行检查时,有14例患者被证明患有高血压。无肾脏病变。动脉高血压常与皮肤微血栓和外周血管病变同时出现。动脉高血压作为APLS的一种心脏病学表现比其他症状更常见。