Komarov V T
Ter Arkh. 1998;70(8):65-6.
The study of incidence of clinico-laboratory signs of antiphospholipid syndrome (APLS) and the results of its treatment in SLE.
Out of 120 patients with verified SLE, 13 (10.8%) had the signs of APLS. They underwent additional tests (platelet and lupus blood anticoagulant assays, assessment of immunity).
APLS treatment consisted of suppression of antiphospholipid antibodies production by glucocorticosteroids and cytostatics, removal of antibodies by means of plasmapheresis, HBO therapy of thromboses and vascular defects. APLS in SLE frequently manifested with arterial thromboses, cerebrovasculitis, livedo, thrombocytopenia, lupus anticoagulant.
Combined treatment of APLS in SLE improves the disease prognosis and prolongs life span.
研究抗磷脂综合征（APLS）的临床实验室指标发生率及其在系统性红斑狼疮（SLE）中的治疗结果。
在120例确诊的SLE患者中，13例（10.8%）有APLS体征。他们接受了额外的检查（血小板和狼疮抗凝物检测、免疫评估）。
APLS的治疗包括用糖皮质激素和细胞抑制剂抑制抗磷脂抗体的产生，通过血浆置换清除抗体，对血栓和血管缺陷进行高压氧治疗。SLE中的APLS常表现为动脉血栓形成、脑血管炎、青斑、血小板减少、狼疮抗凝物。
SLE中APLS的联合治疗可改善疾病预后并延长生存期。
