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特应性皮炎患儿刺激细胞培养物（外周血单核细胞）中的T淋巴细胞亚群（CD4、CD8）、白细胞介素-4和干扰素-γ浓度

T-lymphocyte subpopulations (CD4, CD8), IL-4 and IFN-gamma concentration in stimulated cell culture (PBMC) in children with atopic dermatitis.

作者信息

Boznański A, Machnicki M

机构信息

Department of Pediatric and Allergology Medical Academy, Wrocław.

出版信息

Rocz Akad Med Bialymst. 1995;40(3):474-9.

PMID:8775293
Abstract

The study was carried out on a group of children with atopic dermatitis. We were looking for a correlation between the percentages of CD4, CD8 lymphocytes and IFN-gamma and IL-4 concentrations in stimulated PHA cells cultures (PBMC). On the ground of obtained results, a statistically significant increase of IL-4 concentration in children with atopic dermatitis and a correlation between CD4 cells and IFN-gamma concentration was found.

摘要

该研究针对一组患有特应性皮炎的儿童进行。我们在刺激的PHA细胞培养物（外周血单核细胞）中寻找CD4、CD8淋巴细胞百分比与IFN-γ和IL-4浓度之间的相关性。基于所获得的结果，发现特应性皮炎患儿的IL-4浓度有统计学意义的升高，且CD4细胞与IFN-γ浓度之间存在相关性。

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