Husted J, Gladman D D, Farewell V T, Long J A
University of Toronto, Rheumatic Disease Unit, Toronto Hospital, Canada.
J Rheumatol. 1996 Jun;23(6):1015-9.
To assess the validity of the revised and expanded version of the Arthritis Impact Measurement Scales (AIMS2) in patients with psoriatic arthritis (PsA).
The AIMS2 was administered to all patients attending our Psoriatic Arthritis Clinic between June and December 1993. Clinical and radiological assessments were performed during the clinic visits.
The patient population included 124 patients, 75 men and 49 women with a mean age of 48.4 years and a mean arthritis duration of 14.6 years. Most of the physical function scales as well as the pain and work scales were moderately to highly correlated with clinical measures of function (r = 0.27-0.64) and disease activity (r = 0.28-0.50), but they were not correlated with measures of disease severity. The psychosocial scales were poorly correlated with all clinical measures.
Our data suggest that, like the original AIMS, the AIMS2 is valid for use as an adjunct outcome measure for clinical trials in PsA.
评估修订和扩展版的关节炎影响测量量表(AIMS2)在银屑病关节炎(PsA)患者中的有效性。
1993年6月至12月期间,对所有前往我们银屑病关节炎诊所就诊的患者进行AIMS2评估。在门诊就诊期间进行临床和放射学评估。
患者群体包括124例患者,其中75例男性和49例女性,平均年龄48.4岁,平均关节炎病程14.6年。大多数身体功能量表以及疼痛和工作量表与功能的临床测量指标(r = 0.27 - 0.64)和疾病活动度(r = 0.28 - 0.50)呈中度至高度相关,但与疾病严重程度的测量指标无关。心理社会量表与所有临床测量指标的相关性较差。
我们的数据表明,与原始的AIMS一样,AIMS2可有效用作PsA临床试验的辅助结局指标。