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Allergic contact dermatitis to artificial fingernails prepared from UV light-cured acrylates.

作者信息

Hemmer W, Focke M, Wantke F, Götz M, Jarisch R

机构信息

Dermatologic and Pediatric Allergy Clinic, Vienna, Austria.

出版信息

J Am Acad Dermatol. 1996 Sep;35(3 Pt 1):377-80. doi: 10.1016/s0190-9622(96)90600-3.

Abstract

BACKGROUND

Contact dermatitis from artificial nails made from self-curing acrylic resins is occasionally reported. Recently, UV light-cured products introducing new acrylics have become available.

OBJECTIVE

Our purpose was to identify relevant allergens in commercial light-curing products by patch tests and to evaluate the efficacy of "hypoallergenic" products by inclusion into the test series.

METHODS

Patients wearing photobonded acrylic nails who had perionychial and subonychial eczema were patch tested with an acrylate battery and "hypoallergenic" commercial products.

RESULTS

Triethyleneglycol dimethacrylate, hydroxyfunctional methacrylates, and (meth)-acrylated urethanes proved to be relevant allergens in photobonded nail preparations. Methacrylated epoxy resin sensitization was not observed. All "hypoallergenic" products provoked positive reactions.

CONCLUSION

The omission of irritant methacrylic acid in UV-curable products does not reduce the high sensitizing potential of new acrylates. In contrast to the manufacturers' declarations, all "hypoallergenic" products continue to include acrylate functional monomers and therefore continue to cause allergic sensitization.

摘要

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